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Importantly, GHK-Cu did not negatively impact cell proliferation or NO secretion in these macrophages, suggesting its protective effects were specific to inflammatory pathways rather than general cytotoxicity [1]
10.1016/j.tim.2022.08.003 Trends Microbiol
In other words, it's a medication that targets and binds to the receptors for the GLP-1 peptide, which is part of the bodily systems that regulate hunger and satiation, as well as blood sugar control
Studies using fetal lung fibroblasts found GHK induces dose-response gene expression changes in 329 genes associated with extracellular matrix composition
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