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At low concentrations (0.01 nM), MMP1 and MMP2 gene expression increases, facilitating removal of damaged extracellular matrix proteins

For women, particularly postmenopausal patients with increased cardiovascular risk, this low-dose regimen could serve as a preventive metabolic therapycomplementing hormone optimization, nutrition, and exercise to extend healthspan and protect against heart disease, the leading cause of death in women

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Unlike the older BMI, the BRI better distinguishes between muscle and fat, says Dr Winnett