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Both tirzepatide and semaglutide work by suppressing appetite and slowing down the movement of food through your digestive system

A study presented at the 2025 American Academy of Orthopaedic Surgeons meeting found that stopping semaglutide two weeks before hip and knee replacement was associated with lower rates of anesthesia-related complications

This dual GIP and GLP-1 receptor agonist, extensively studied in trials, demonstrates significant efficacy in body weight reduction and management of weight-related complications