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[73] [74] [75] It is synthesized by some bacteria in the gut microbiota in humans and other animals, but it has long been thought that humans cannot absorb this as it is made in the colon, downstream from the small intestine, where the absorption of most nutrients occurs
It is one of the most widely referenced compounds in tissue repair and regeneration research, studied extensively for its interactions with growth hormone receptor pathways, nitric oxide systems, and angiogenesis mechanisms
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