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The total round-trip if you take a 3-month break is roughly 6 months back to your prior body composition
Similar to the periplasm, the GSH:GSSG ratio in the ER is lower (3:1 to 1:1) compared to the cytosol (100:1), resulting in a more oxidizing environment (Hwang et al., 1992)
In persons with normal weight, the contribution of fat-free mass loss often exceeds 35 percent of total weight loss, and weight regain promotes relatively more fat gain
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