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GLP-1 Agonists Enhance Cardiac Metabolism in Ischemia Proteomic Profiling of GLP-1-Mediated Cardioprotection in a Large Animal Model of Chronic Coronary Artery Disease Clark Zheng, MD 1, Christopher Stone, MD 1, Kelsey Muir, MD 1, Dwight Harris, MD 1, Frank W
We found that glutathione and thioredoxin, the major thiol antioxidants, and glutathione and thioredoxin reductases, the enzymes responsible for maintaining them in a reduced state, fell substantially in rodent bone marrow after ovariectomy and were rapidly normalized by exogenous 17- estradiol
Considering the stability problems of liposomes, an effective alternative is proliposomes, a formulation in which liquid liposomes are transformed into a solid state (Payne et al., Citation1986)