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In a multicenter randomized controlled trial, 306 deceased donors were randomized to receive corticosteroids (1000 mg of methylprednisolone) or placebo prior to organ procurement: the rate of biopsy-proved rejection at 3 months as well as 5-year graft survival did not significantly differ between the pre-treated and placebo groups, suggesting that this approach did not impact on long-term clinical outcomes (137)
It is not approved for human consumption or therapeutic use
Decreasing alcohol intake can decrease phenotypic expression of disease
These trials enrolled a total of 57,754 people
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