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Individuals with excoriation (skin-picking) disorder pick at their skin which often results in lesions, infections, scarring and all too often, shame
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For semaglutide specifically, the SmPC advises discontinuation at least 2 months before a planned pregnancy due to its long half-life
This protective effect involves TUG1 binding to the RNA splicing factor 1, which stabilizes ACSL4 mRNA- a key driver of lipid peroxidation- highlighting a novel axis for therapeutic intervention
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