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Side effects such as drowsiness, dizziness, nausea and vomiting, dry mouth, drug high, and others were reported in studies included in the systematic review, though none were severe
The peptide corresponds to an active motif derived from thymosin beta-4 that is known to bind G-actin and regulate actin polymerization dynamics
Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age
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