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We suggest a new role of metformin in the glutamate system, whereby it protects the hippocampus against the derangements of the glutamatergic system induced by MG, possibly by phosphorylation via PKC (4)

There have been some reports of mild adverse effects, such as headaches, dizziness, or nausea

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Steps Toward a Molecular Grammar For Learning: Explorations Into The Nature of Memory