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This metabolic shift occurs due to the peptides action on the nicotinamide methylation pathway , which increases intracellular NAD+ availability, facilitating greater oxidative metabolism
Treatment with liraglutide reduced the TG-induced accumulation of these ER stress-related proteins and subsequently decreased ER stress related-apoptosis in chondrocytes
This stress can damage cells and even cause harm at a DNA level, leading to issues with copying genetic data
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