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Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism

Instead of using a single peptide to target one issue, KLOW combines four distinct peptides to create a more comprehensive and powerful effect

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Collectively, our observations indicate a significant involvement of cryptic glycan epitopes in immunological recognition of senescent beta cells, and that clonal composition of the GlcNAc-specific B cell repertoire during early life can significantly influence immune responsiveness to Type 1 diabetes autoantigens, Kearney said