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Guo Z, Lucchetta E, Rafel N, Ohlstein B (2006) Maintenance of the adult Drosophila intestine: all roads lead to homeostasis
According to Lillys release, the trial met its primary endpoint: participants titrating up to the highest orforglipron dose lost 27.3 lb (12.4%) of body weight at 72 weeks versus about 0.9% weight loss with placebo
This delivery approach is consistent with standard probiotic supplement engineering practices
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