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Therefore, genetic ablation or pharmacological inhibition of Parp-1 enhances the Sirt1 activity through restoring the NAD + content, providing a protection benefit for various tissues, including the liver, muscle and brown adipose tissue
Therefore, 26 participants in the LC group and 24 participants in the placebo group completed the trial but data analysis was based on ITT
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The article lists body composition, specifically lean versus fat mass, as a maintenance biomarker and says preserving muscle during weight loss predicts better metabolic stability and lower rebound risk after treatment
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