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Les A.N.C
Townsend et al., 2003)
GH axis stimulation in pre-clinical ageing models: Studies examining GHRH analogue + GHRP combinations in aged rodent models documented restoration of GH pulse amplitude and IGF-1 levels toward younger values with findings establishing that somatotroph GH secretory capacity is largely preserved in aged animals despite reduced hypothalamic GHRH drive, and that pharmacological dual-pathway somatotroph stimulation can overcome age-associated GH decline
Regulatory effect of hsa-miR-5590-3P on TGF signaling through targeting of TGF-R1, TGF-R2, SMAD3 and SMAD4 transcripts
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