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Compare this to the side effect profile of pharmaceutical GLP-1 medications , where nausea affects 40 to 50 percent of users, vomiting occurs in 20 to 30 percent, and constipation is reported by a significant proportion of people throughout treatment

That really captures how little innovation theres been. Reville says that GLP-1s have many advantages: They appear to work across all substances, patients dont have to be abstinent to start treatment, and its easy to self-administer the weekly dose