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The search included terms such as small molecule GLP-1 receptor agonists, oral GLP-1 receptor agonists, Danuglipron, Orforglipron, and Aleniglipron. Additionally, information on ongoing clinical trials involving small molecule GLP-1 receptor agonists was retrieved from the ClinicalTrials.gov database using the same keywords
This compound serves as a valuable tool for researchers studying the mechanisms of glucose-dependent insulin secretion, appetite regulation, and gastric emptying
Biological processes, including negative regulation of lipid storage (GO:0010888), adipocyte differentiation (GO:0045599), and apoptotic process (GO:0043066), and positive regulation of transcription by RNA polymerase II (GO:0045944) (Fig
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