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Antioxidant Detection Acetylcholine Esterase (AChE): AChE activity was measured according to Ellman et al

Together, this cross-species comparison reveals conserved remodeling in MS and toxin demyelination models, including upregulation of core DAM signature genes and suppression of homeostatic microglial identity, though LPC notably reflects a shift toward lysosomal myelin debris clearance, whereas CPZ reflects chronic stress and metabolic adaptation

Additionally, surgery often involves anesthesia drugs that can directly or indirectly affect mitochondria e.g

For the scVI model, the batch key was set to the sample_id (representing each individual sample), and RNA count and percent mitochondrial count were given as continuous covariates