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The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

MDM2-MDM4 RING inhibitors (MMRi) such as MMRi62 and MMRi71, which were initially designed to inhibit the MDM2MDM4 interaction to stabilize p53 [137], have recently been demonstrated to trigger the death of cancer cells

Tumor necrosis factor-alpha (TNF-alpha), a cytokine involved in systemic inflammation, along with matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) enzymes that break down extracellular matrix proteins might potentially influence both the inflammatory processes and the remodeling of tissues

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