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0.777) ( In 2018, a study was published in which B-cell activity markers and organ involvement in pSS were considered ( In 2019, another retrospective study was published which evaluated epidemiological factors such as age, ethnicity, gender, and latitude and their association with organ involvement in pSS ( For what concerns the latitude at which study participants lived, or North-South gradient, patients who lived in southern regions were significantly more affected by systemic involvement of pSS, including renal disease

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A patient completes an online health assessment, a licensed provider reviews, and if appropriate a prescription is issued and sent to a partner pharmacy for fulfillment