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Tirzepatide is FDA-approved for weight loss under the brand name Zepbound and is available in Canada through Mounjaro (approved for type 2 diabetes) with growing off-label weight management use

However, the studies mentioned above commonly lack a comprehensive description of the complete pharmacokinetic profiles of the monomers investigated

JAMA Cardiol 10(1):9698 Haddy N, Jourdain H, Desplas D, Bertrand M, Jabagi MJ, Rives-Lange C, Zureik M (2025) Use of semaglutide (Wegovy) in adults in France: A nationwide drug utilization study

This includes determining the appropriate dosage, administration method, and monitoring protocols