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The PI3K/AKT pathway, frequently hyperactivated in cancers due to mutations like those in PIK3CA, drives metabolic reprogramming and enhances antioxidant defenses by stimulating GSH biosynthesis [49]
Epitalon also appears to modulate gene expression , particularly those related to oxidative stress response and inflammation both of which are critical components in the development of age-associated diseases
Effect on Oxidative Stress and Antioxidant Defense The effect of oral CoQ10 conventional form and liposomal formulation on SOD, CAT, GSH, NO, MDA and protein content in the brain tissue homogenate of mice was assessed
2012;14:10e26
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