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No, GLP-1 receptor agonists are not licensed or recommended for treating high cortisol levels or Cushing's syndrome

doi: 10.1146/annurev-nutr-071714-034330 58 SpinnekerASolaRLemmenVCastilloMJPietrzikKGonzlez-GrossM

37 Wulffel, M.G., et al., Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial

The wide spectrum of outcomes and demographic gradients observed emphasize the urgent need for precision approaches to obesity treatment and highlight opportunities for next-generation incretin therapeutics informed by real-world response phenotypes