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doi: 10.2337/db21-0459 70 ChengWGordianDLudwigMQPersTHSeeleyRJMyersMGJr

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For example, in the case of amylin biology, significant translational gaps between rodent and human systems persist, the optimal receptor selectivity profile for clinical use remains unclear, and molecules continue to advance in clinical development despite these uncertainties (Hollander et al., 2020)