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Baseline patient characteristics, full frequencies of side effects and study structure are not described in detail
(1) Neurodevelopmental Homeostasis: In the healthy state, mitochondrial oxidative phosphorylation (Complexes IV) supports efficient ATP generation, redox stability, and formate flux from the mitochondrial folate cycle (via SHMT2, MTHFD2)
Perhaps most importantly, appetite becomes much easier to manage, making sustainable lifestyle changes possible
Sakata, Y
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