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143,144 The mutated IDH1 and IDH2 proteins are endowed with a novel ability to catalyze the reduction of -KG to generate a rare metabolite, 2-hydroxyglutarate (2-HG), while consuming NADPH

2g), correlating with increased mitochondrial abundance and activity

Effects of BARLEYmax and high-beta-glucan barley line on short-chain fatty acids production and microbiota from the cecum to the distal colon in rats

4.6 Clinical implications and therapeutic perspectives in fungal infections Mitochondrial dysfunction during fungal infections contributes to both immune dysregulation and tissue damage, presenting opportunities for therapeutic intervention