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Adequate fibre prevents it, but adding too much too fast worsens bloating

Diabetes GLP-1s perform better but still leak demand: Diabetes-indicated GLP-1s show higher retention (24% at one year) and face fewer access hurdles due to broader coverage and disease framing, yet 76% of demand remains unmet

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Retatrutide is also being investigated for its impact on cardiovascular risk factors and other metabolic health markers, including its potential role in the prevention or management of cardiovascular disease