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Compounded semaglutide is still a subcutaneous injection, but is handled using syringes instead of spring-loaded devices
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FLOW (Perkovic et al., 2024)
Cardiovascular safety data from published trials showed reductions in systolic blood pressure (ranging from 4.3 to 7.9 mmHg depending on dose) and diastolic blood pressure (2.3 to 4.6 mmHg reductions)
Those who were concurrently using GLP-1 receptor agonists had a 48% lower rate of UTIs (8.8% versus 13.3%) and a 74% lower rate of urinary retention compared to those not on GLP-1 therapy
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