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Three reasons compound
Fatigue (common and usually mild) Some patients feel more tired than usual during the first days at a new dose
The medication carries a risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
The most common user-reported experience: Temporary skin dryness in week 1 (resolves by week 2) Occasional injection site redness (standard for any subQ peptide) Some users report increased hair growth, including in unintended areas at higher doses At doses above 34 mg/day, some protocols note headaches, but this is well above standard dosing
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