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A peptide that modulates VEGFR2 in a cell culture dish, or heals a rat tendon at 10 mcg/kg IP injection, has not been shown to survive oral delivery in a human at 500 mcg and reach musculoskeletal tissue at any meaningful concentration
(8) Reports on the -MSH family more broadly also suggest that Lys-Pro-Val may ease fibroblast stress in dermal cell injury models, which points toward a possible supporting role in structural repair
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