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The molecular mechanism underlying lactate-induced downregulation of ACSL4 via MCT1 remains incompletely elucidated, although accumulating evidence suggests a potential involvement of the lactate-induced STAT3 signaling pathway (197,198)
This multi-targeted approach is particularly relevant for patients whose gut barriers have been compromised by the complex pathophysiology of chronic illness
Eat smaller, more frequent meals: If your appetite is low, try 45 mini meals every 34 hours instead of 3 large meals
doi:10.1016/j.obpill.2024.100127 Popoviciu MS, Pduraru L, et al
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