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The market authorization covers two presentations 2 mg / 3 mL (0.68 mg/mL) and 4 mg / 3 mL (1.34 mg/mL) matching the concentration and fill-volume profile of the reference product, which patients and prescribers in Canada are already familiar with

Regul Pept 118:1118 Muscelli E, Mari A, Casolaro A et al (2008) Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

This serves to further consolidate Eli Lillys protection around the active ingredient tirzepatide and, therefore, its products Mounjaro and Zepbound

Therefore, the decrease in both the reaction rate and yield could be caused by a decrease in NsPCS activity