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Its plasma concentration decreases with age: approximately 200 ng/ml at age 20 versus 80 ng/ml at age 60, correlating with the decline in regenerative capacity
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Another way to deliver HGF is the use of hydrogel carriers, which are useful in supporting neurogenesis (Nakaguchi et al., 2012) and mitigate apoptosis and autophagy (Shang et al., 2010) after stroke in mice models
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