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Finally, heterogeneity in study design, included populations (often mixing children and adolescents), supplement dosages and formulations, and even comparators (sometimes active placebos such as canola oil) complicates meta-analysis and explains divergent results, especially in functional gastroenterology (132137)

BPC-157

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Exenatide formulations show variable nausea rates: the twice-daily immediate-release preparation (Byetta) tends to produce higher rates of nausea (approximately 3050%), whilst the once-weekly extended-release formulation (Bydureon) demonstrates improved tolerability with nausea rates of approximately 1424%, according to their respective SmPCs