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The manufacturers of GLP1-RAs typically recommend lowering doses of insulin and insulin secretagogues at the initiation of GLP-1 RA treatment to reduce the risk of hypoglycemia
Although it is well supported that ketogenesis from MCFA in the liver supplies the brain with alternative fuel with certain procognitive benefits, at this point, it is still an open question to what extent and which beneficial effects of MCFAs are mediated through KB and which through MCFA
Antioxidant enzymes such as superoxide dismutase (SOD) play a key role in diminishing oxidative stress
Also, one study 12 reported only mild AEs with ALC (dry mouth, n=1
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