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For atherosclerotic events, Jardiance showed similar risk rates to both DPP-4s and GLP-1s
The requirement of 6-month continuous enrollment during the 6-month pre-index and follow-up periods may limit the generalizability of outcomes for patients who disenrolled within 6 months after the first observed tirzepatide-related claim
Instead, compounded GLP-1 + GIP alternatives may be prescribed when clinically appropriate and legally permissible
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