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The short version If you want the headline before the detail: Ozempic/Wegovy works well, widely available on prescription, ~15% weight loss Mounjaro works better, widely available on prescription, ~2127% weight loss Retatrutide works best, not yet prescription-available in UK, 19% at 4mg rising to 28.3% at the 12mg trial dose If maximum results are your priority and you're willing to self-manage, Retatrutide wins
Common justifications include allergy or sensitivity to an inactive ingredient in the commercial product, need for a specific dose not available commercially, or documented medical need for the additional niacinamide component
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Variety In the past, Life Extension only sold its own products, but it has since expanded to include offerings from 16 other supplement and wellness brands
