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Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice

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Molecular pathway diagrams and rodent healing results are useful for generating scientific hypotheses, but they arent evidence that a product improves outcomes in human patients

Amazingly, those benefits are seen at a dosage that is 10 times lower than that required with NAC