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The PP family of proteins bind to a family of receptors that were originally characterized as NPY receptors
GLP-1 RA studies in psoriasis demonstrate consistent bias in patient selection, with the majority of studies targeting patients with comorbid T2D and/or obesity
10.1038/sj.ijo.0800818 73 PalmiterR
In addition, exenatide was shown to activate GLP-1R and inhibit the PI3K/AKT pathway to inhibit the growth, migration, and invasion of ovarian cancer cells, and promote cell apoptosis, thereby producing anticancer effects on diabetic patients with ovarian cancer (218)
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