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10.1016/j.neuropharm.2023.109716 Neuropharmacology 37 ZhaiY.LuK.YuanY.ZhangZ.XueL.ZhaoF.et al
First, a recent study showed that GIPR antagonism reduces insulin secretion during a meal-tolerance test in subjects with T2D 37,38
For example, in the SELECT trial (17,600 patients with cardiovascular disease and obesity but without T2D), weekly subcutaneous Semaglutide (2.4 mg) reduced the risk of major adverse cardiovascular events (MACE heart attack, stroke, or cardiovascular death) by 20% compared to placebo (HR 0.80
An no hay una clara explicacin para los resultados
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