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Aspiration Risk: A critical 2026 safety update from the American Society of Anesthesiologists notes that Semaglutide slows stomach emptying so significantly that users must stop the medication 12 weeks before any surgery to prevent inhaling stomach contents while under anesthesia
The risk of weight regain needs to be addressed, perhaps through individualized dose-tapering strategies, given the increasing popularity of these agents for weight loss and the high discontinuation rates
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