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As a result, current clinical guidelines for T2DM, kidney disease, and cardiovascular care strongly recommend the use of GLP-1RAs and SGLT2is in patients with T2DM who have, or are at high risk for, atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), or chronic kidney disease (CKD)

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Some patients with lymphedema have few symptoms, and can easily do different degrees of physical activity, while others feel the strain, experience increased swelling with minimum effort, or even suffer varying degrees of disability and severe complications

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European Journal of Pharmaceutics and Biopharmaceutics 98 , 4756, (2016)

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