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for example, owing to adverse effects, patient preference, cost pressures or formulary decisions
For researchers exploring multiple options, understanding these differences helps in designing rational protocols
Chan HP, et al
Nrf2 overexpression starts out playing a protective role in cancer, but ultimately encourages disease progression and metastasis, while mutations in Keap1 have been linked to a poor prognosis in individuals with advanced NSCLC receiving treatment [10]
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