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In SUSTAIN 6 and PIONEER 6, both powered to demonstrate noninferiority (upper 95% confidence interval [CI] of the hazard ratio [HR] 7% and at high risk of CV events, defined as: i) aged 50 years with established CVD (previous CV, cerebrovascular, or peripheral vascular disease), chronic heart failure (HF) (New York Heart Association [NYHA] class II or III), or chronic kidney disease (CKD) stage 3

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How Clinicians Decide Whether Combination Treatment Is Appropriate Clinicians determine whether combination treatment is appropriate through structured evaluation rather than default prescribing

Like semaglutide, tirzepatide helps you lose weight by lowering blood sugar, increasing feelings of fullness, and slowing down digestion