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In our experiment of endothelium-dependent vasodilation, 10 9 10 7 mol/L acetylcholine (Ach) stimulation decreased the vascular tension of aortic rings in a dose-dependent manner in wild-type mice under normal diet condition (Fig

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Administration: Subcutaneous or intramuscular injection 5-10mg daily for 10-20 days, repeated 2-4 times yearly in cycles