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Metastasis is the main reason for its which results in high mortality of the patients (Bray et al., The HGF/c-Met axis has been implicated as a crucial modulator of metastasis-associated signal transduction pathways in GC progression

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Using it for a multi-dose vial is asking for bacterial growth in a protein-rich solution

Meanwhile, colistin showed weak interactions with both phospholipids, probably because the calcium ions suspended in the solution might repel the positive charges of the side chains of the colistin residues