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In this population, weekly treatment with the glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide leads to both reduced body fat and increased lean body mass, according to a 2021 study presented virtually at the Endocrine Societys annual meeting

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(2019) Nat Rev Cardiol | doi: 10.1038/s41569-018-0108-7 Wall BT, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL.: Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans