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Medical oversight and appropriate dosing are essential

While peroxidases were known at the time, and their possible involvement in ascorbate oxidation previously noted (Mapson and Goddard 1951), the physiological functions of such enzymes were considered to be as much in H 2 O 2 -dependent oxidations as reductant-dependent H 2 O 2 removal

10.1111/j.1939-1676.2000.tb02283.x