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Despite growing recognition of spatial and temporal heterogeneity under combined abiotic stresses, understanding of simultaneous biotic-abiotic stress remains comparatively limited
18 In kidney injury, extracellular vesicles and secreted lipid mediators are sufficient to synchronize ferroptotic death across spatially contiguous tubular epithelial cells, thereby contributing to a self-amplifying wave of tubular death during the transition from acute kidney injury to chronic kidney disease
A 2025 review by Ro noted that excess sodium can actually harm vascular health over time
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