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Even though GSH levels were below the threshold for rescuing WT cell growth in cystine-free conditions, co-culturing with GGT1 + cells led to complete rescue of WT cell growth (Fig

found that glutamine and its dipeptides restored oxidative metabolism in neonatal hepatocytes impaired by septic mediators (H 2 O 2 , NO), likely through boosting glutathione synthesis rather than the Krebs cycle

Heres how it works: Neutralizing Free Radicals : Glutathione directly neutralizes reactive species like superoxide anions and hydroxyl radicals, preventing them from damaging cellular structures like lipids, proteins, and DNA

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